Table 2 Comparison of demographic and clinical characteristics of hospitalized patients with COVID-19 according to death.

From: Sex-based differences in mortality among a large cohort of hospitalized patients with RT-PCR-confirmed SARS-CoV-2 infection at five different pandemic waves in Northern Iran

Variables

Total

Death; %

Crude logistic regression

P-value

OR

95% CI

Lower

Upper

Sex

Female

24,212

7.9

Ref.

Ref.

Ref.

Ref.

Male

20,332

9.8

1.26

1.18

1.34

< 0.001

Age group

< 20

974

2

Ref.

Ref.

Ref.

Ref.

20–29

2000

2

1.05

0.61

1.82

0.857

30–39

6738

2.4

1.22

0.76

1.98

0.412

40–49

8074

3.5

1.83

1.14

2.92

0.012

50–59

9313

6.5

3.52

2.22

5.58

< 0.001

60–69

8966

11.1

6.25

3.95

9.88

< 0.001

70–79

5298

18.1

11.10

7.01

17.57

< 0.001

≥ 80

3181

26.4

18.06

11.39

28.64

< 0.001

DM

No

36,554

7.7

Ref.

Ref.

Ref.

Ref.

Yes

7990

13.7

1.91

1.77

2.05

< 0.001

HTN

No

35,930

7.5

Ref.

Ref.

Ref.

Ref.

Yes

8614

13.9

1.97

1.84

2.12

< 0.001

Smoking

No

44,014

8.8

Ref.

Ref.

Ref.

Ref.

Yes

530

9.2

1.06

0.79

1.43

0.691

Cancer

No

44,015

8.6

Ref.

Ref.

Ref.

Ref.

Yes

529

18.9

2.47

1.98

3.07

< 0.001

HIV/AIDS

No

44,521

8.8

Ref.

Ref.

Ref.

Ref.

Yes

23

17.4

2.19

0.75

6.45

0.153

Heart disease

No

38,716

7.7

Ref.

Ref.

Ref.

Ref.

Yes

5828

16.1

2.31

2.14

2.51

< 0.001

CKD

No

43,841

8.5

Ref.

Ref.

Ref.

Ref.

Yes

703

25

3.60

3.02

4.28

< 0.001

Asthma

No

43,690

8.7

Ref.

Ref.

Ref.

Ref.

Yes

854

10.7

1.25

1.00

1.55

0.048

COPD

No

44,220

8.7

Ref.

Ref.

Ref.

Ref.

Yes

324

21.6

2.90

2.22

3.79

< 0.001

Opioid user

No

43,899

8.6

Ref.

Ref.

Ref.

Ref.

Yes

645

19.1

2.50

2.05

3.05

< 0.001

CND

No

44,092

8.7

Ref.

Ref.

Ref.

Ref.

Yes

452

15.3

1.89

1.46

2.45

< 0.001

Comorbidity

No

28,237

6.1

Ref.

Ref.

Ref.

Ref.

Yes

16,307

13.3

2.36

2.21

2.52

< 0.001

NoC

0

28,237

6.1

Ref.

Ref.

Ref.

Ref.

1

9040

10.9

1.87

1.73

2.03

< 0.001

2

5236

15.3

2.78

2.54

3.04

< 0.001

≥ 3

2031

19

3.59

3.18

4.05

< 0.001

Peak of COVID

1

1826

18.2

3.05

2.67

3.48

< 0.001

2

7749

11.3

1.75

1.60

1.92

< 0.001

3

9025

10.3

1.57

1.43

1.71

< 0.001

4

7107

6.9

1.01

0.91

1.12

0.870

5

18,837

6.8

Ref.

Ref.

Ref.

Ref.

  1. CKD: Chronic Kidney Disease, COPD:, CND: Chronic Neurological Disorder, NoC: Number of Comorbidities, DM: Diabetes Mellitus, HTN: Hypertension, HIV: Human Immunodeficiency Virus, AIDS: Acquired Immunodeficiency Syndrome, OR: Odds Ratio, CI: Confidence Interval.