Fig. 4 | Scientific Reports

Fig. 4

From: Evaluating cell-specific gene expression using single-cell and single-nuclei RNA-sequencing data from human pancreatic islets of the same donors

Fig. 4

Loss of Zfp385d results in perturbed insulin secretion in 832/13 INS1 cells. The panels show (a) qPCR quantification of siRNA-mediated knockdown of Zfp385d (n = 5) (siZfp385d:1) and 6 (siZfp385d:2)). (b) Beta cells deficient for Zfp385d exhibit perturbed glucose-stimulated insulin secretion (n = 6). siNC: negative control siRNA. *p < 0.05 and **p < 0.01, based on one-tailed (a) and two-tailed (b) paired t-tests.

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