Table 2 Areas under the curve of various parameters for predicting 28-day all‐cause mortality or poor neurological prognosis in patients after ROSC.
From: Circulating CD24/Siglec-10 biomarkers predict post-resuscitation outcomes in a cardiac arrest cohort
28-day all-cause mortality | 28-day poor neurological prognosis | |||||
|---|---|---|---|---|---|---|
AUC | 95%CI | P | AUC | 95% CI | P | |
sCD24D1 | 0.764 | 0.675–0.853 | 0.000 | 0.812B | 0.726–0.897 | 0.000 |
sCD24D3 | 0.852 | 0.762–0.942 | 0.000 | 0.814C | 0.717–0.912 | 0.000 |
sCD24D7 | 0.998 | 0.991-1.000 | 0.000 | 0.819D | 0.695–0.943 | 0.000 |
sSiglec-10D1 | 0.555 | 0.414–0.695 | 0.385 | 0.549 | 0.381–0.717 | 0.517 |
sSiglec-10D3 | 0.763 | 0.641–0.883 | 0.000 | 0.841 | 0.739–0.943 | 0.000 |
sSiglec-10D7 | 0.824 | 0.706–0.943 | 0.000 | 0.722 | 0.573–0.871 | 0.012 |
Sialic acidD1 | 0.547 | 0.433–0.662 | 0.451 | 0.578 | 0.446–0.709 | 0.303 |
Sialic acidD3 | 0.711 | 0.590–0.831 | 0.003 | 0.672 | 0.542–0.802 | 0.031 |
Sialic acidD7 | 0.822 | 0.700-0.944 | 0.001 | 0.722 | 0.573–0.871 | 0.012 |
NeuraminidaseD1 | 0.510 | 0.392–0.627 | 0.877 | 0.545 | 0.410–0.660 | 0.550 |
NeuraminidaseD3 | 0.707 | 0.575–0.838 | 0.003 | 0.692 | 0.531–0.853 | 0.016 |
NeuraminidaseD7 | 0.696 | 0.528–0.864 | 0.034 | 0.613 | 0.449–0.778 | 0.203 |
NSED1 | 0.899 | 0.838–0.960 | 0.000 | 0.853 | 0.780–0.927 | 0.000 |
NSED3 | 0.927 | 0.865–0.989 | 0.000 | 0.873 | 0.780–0.954 | 0.000 |
NSED7 | 0.998 | 0.991-1.000 | 0.000 | 0.870 | 0.760–0.981 | 0.000 |
IL-6D1 | 0.742 | 0.638–0.846 | 0.000 | 0.711 | 0.599–0.824 | 0.005 |
IL-6D3 | 0.757 | 0.652–0.862 | 0.000 | 0.712 | 0.592–0.831 | 0.008 |
IL-6D7 | 0.882 | 0.787–0.978 | 0.000 | 0.650 | 0.489–0.812 | 0.091 |
sCD24D1+ IL-6D1 | 0.875Aa | 0.810–0.940 | 0.000 | – | – | – |
sCD24D1 + NSED3 | – | – | – | 0.938Ee | 0.883–0.993 | 0.000 |
