Fig. 3

Effects of PCB 138 and PCB 153 on THP-1 cells viability and hamp gene expression. A) Cell vitality was assessed using the MTT assay. PCBs were used at different concentrations (1 µM, 10 µM, 50 µM and 100 µM). The experiment was seeded in triplicate. B) hamp gene expression was analyzed by qPCR after treatment with 50 µM of each PCB. Three independent replicates were used for relative expression data analysis. Statistical significance was performed using One-way ANOVA with Dunnett’s multiple comparisons test for both experiments (* = p < 0.05, ** = p < 0.01, *** = p < 0.001). This figure was generated with BioRender.