Table 2 List of 2D-electrophoresis differentially expressed proteins identified through Maldi-TOF analysis.

From: Dictyostelium exhibits PCB-induced impairment of proliferation, development and stress response, emerging as model for conserved environmental toxicity

Spot number

Differentially expressed identified proteins

Relative expression

GO

8

ARGE (Acetylornithine deacetylase)

Upregulated

arginine/ornithine biosynthesis

9

CAD1 (Calcium-dependent cell adhesion molecule 1)

Upregulated

sorocarp development, cell–cell adhesion

10

CGL (Cystathionine gamma-lyase)

Upregulated

cysteine/L-methionine biosynthesis

11

METK (S-adenosylmethionine synthase)

Upregulated

S-adenosylmethionine synthesis

13

PAP1A (Polyadenylate-binding protein 1-A)

Downregulated

mRNA processing

15

HS7C2 (Heat schok cognate 70 kDa protein 2)

Upregulated

stress response

19

CAP (Adenylyl cyclase-associated protein)

Upregulated

aggregation, sorocarp development

20

EF1A1 (Elongation factor 1-alpha)

Downregulated

actin filament bundle assembly

22

MDH2 (probable Malate dehydrogenase 2, mitochondrial)

Upregulated

oxidation–reduction process, TCA cycle

22

MSDH (probable Methylmalonate-semialdehyde dehydrogenase, mitochondrial)

Upregulated

oxidation–reduction process, valine degradation