Fig. 1 | Scientific Reports

Fig. 1

From: Test–retest reliability of intra-epidermal electrically evoked potentials in comparison with other modalities and across stimulation intensities

Fig. 1

Experimental design of Experiment 1 and Experiment 2. In Experiment 1, 26 participants were recruited, while in Experiment 2, 30 participants were recruited. Both experiments consisted of two identical visits two weeks apart. Additionally, pain-related evoked potentials (PREPs), pain perception in a numerical rating scale, and quality of sensation in response to noxious stimuli were assessed in both experiments. In Experiment 1, the volar forearm was stimulated with contact heat, pinprick, and intra-epidermal electrical stimulation (IES) in a randomized order. In Experiment 2, the volar forearm was stimulated with IES applying different stimulation intensities in a randomized order. EDT electrical detection threshold, IES intra-epidermal electrical stimulation, PREPs pain-related evoked potentials.

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