Fig. 3
From: Elucidating the underlying mechanism of mechanical stress-induced impact on mRNA-LNP structure
Experiments to confirm the presence of unencapsulated mRNA in the 240 min shaking samples. (a) image of a stained sample before RNase A treatment (similar to the lower-right image in Fig. 2). (b) image of a stained sample after RNase A treatment. The fiber-structure completely disappears after RNase A treatment. (c) Image of a stained sample pre-treated with RNase inhibitor followed by RNase A treatment whereby the fiber-like structure remains. Scale bars represent 100 nm.
