Fig. 8

Flow cytometry analysis for evaluating CD19- and CD3ε-targeting ability of p-blinatumomab. (a,b) Binding affinities of BLINCYTO and p-blinatumomab to (a) CD19-overexpressing Raji cells and (b) CD3ε-overexpressing Jurkat cells. The dissociation constants (Kd) were calculated using non-linear regression analysis. All values are expressed as the mean ± standard deviation (SD) based on three independent experiments (n = 3).