Fig. 3
From: STAT1 and m6A-mediated IL15RA upregulation promotes metastasis via ZEB1/NF-κΒ axis in ccRCC

Immunotherapy prediction, mutation and other modification analysis of IL15RA. (A). Immunotherapy response of IL15RA in vivo tumor model in murine ICB therapy cohorts. (B). Immunotherapy response of IL15RA in vitro cell lines. (C). The association between IL15RA and IPS scores using the TCIA database. (D). Biomarker relevance of IL15RA compared to standardized biomarkers on tumor immune evasion in ICB therapy cohorts. (E). Mutation and other modification analysis of IL15RA.Genetic alteration frequency of IL15RA. (F). Correlation between methylation and IL15RA expression. (G). Expression correlation of DNA methyltransferase genes with IL15RA. (H). Correlation of CNV with IL15RA expression. (I). Correlation between mismatch repair genes and IL15RA expression. (J). Correlation analysis of IL15RA and m1A genes. (K). Correlation analysis of IL15RA and m6A genes. (L). Correlation analysis of IL15RA and m5C genes. *P < 0.05; **P < 0.01; ***P < 0.001.