Fig. 4
From: Extracellular RNA as a molecular driver and therapeutic target in abdominal aortic aneurysms
Effects of RNase A treatment on aortic gene expression in the AngII AAA model. Abdominal aortic tissues from PBS- and RNase A-treated mice (n = 8 per group) were harvested at the experimental end point on day 28 for RNA extraction, reverse transcription, and quantitative PCR analysis. Genes were grouped into A SMC markers, B granulocyte lineage–associated genes, and C monocyte lineage–associated genes. Values are presented as individual log transformed data points with group means ± SE indicated by gray lines. Statistical comparisons between groups were performed using the Mann–Whitney U test. Gene names, synonyms, and primer details are provided in Supplementary Table 2.
