Table 1 Protein kinase inhibitor sets.
Abbreviation | Protein kinase | # PKIs | # Actives |
|---|---|---|---|
AGC Ser/Thr protein kinase family | |||
PKN2 | Serine/threonine-protein kinase N2 | 699 | 183 |
PRKX | cAMP-dependent protein kinase catalytic subunit PRKX | 733 | 197 |
Tyr protein kinase family | |||
BLK | Tyrosine-protein kinase Blk | 635 | 216 |
CAMK Ser/Thr protein kinase family | |||
DAPK3 | Death-associated protein kinase 3 | 892 | 239 |
MELK | Maternal embryonic leucine zipper kinase | 564 | 171 |
MKNK2 | MAP kinase-interacting serine/threonine-protein kinase 2 | 665 | 195 |
STK17A | Serine/threonine-protein kinase 17 A | 576 | 186 |
CMGC Ser/Thr protein kinase family | |||
CDK8 | Cyclin-dependent kinase 8 | 474 | 195 |
CLK2 | Dual specificity protein kinase CLK2 | 855 | 231 |
DYRK1A | Dual specificity tyrosine-phosphorylation-regulated kinase 1 A | 1028 | 336 |
HIPK2 | Homeodomain-interacting protein kinase 2 | 669 | 204 |
HIPK4 | Homeodomain-interacting protein kinase 4 | 599 | 151 |
STE Ser/Thr protein kinase family | |||
MAP4K2 | Mitogen-activated protein kinase kinase kinase kinase 2 | 858 | 245 |
MAP4K4 | Mitogen-activated protein kinase kinase kinase kinase 4 | 971 | 363 |
MAP4K5 | Mitogen-activated protein kinase kinase kinase kinase 5 | 666 | 238 |
MINK1 | Misshapen-like kinase 1 | 644 | 165 |
SLK | STE20-like serine/threonine-protein kinase | 677 | 221 |
STK3 | Serine/threonine-protein kinase 3 | 796 | 204 |
TKL Ser/Thr protein kinase family | |||
LIMK1 | LIM domain kinase 1 | 850 | 227 |
