Table 2 Univariable and multivariable Cox regression analyses for identifying factors associated with OS before PSM.

From: Added prognostic value of temporal muscle thickness in glioblastoma with age-stratified analysis

 

Univariable

Multivariable without TMT

Multivariable with TMT

HR (95% CI)

P value

HR (95% CI)

P value

HR (95% CI)

P value

TMT

1.48 (1.11–1.97)

0.007**

  

1.42 (1.06–1.90)

0.02*

SEX

0.70 (0.54–0.90)

0.001**

0.81 (0.62–1.08)

0.138

0.82 (0.63–1.09)

0.172

AGE

1.02 (1.01–1.03)

0.006**

1.02 (1.01–1.03)

0.001*

1.02 (1.01–1.03)

0.001**

KPS

0.98 (0.97–0.99)

0.001**

0.98 (0.97–0.99)

0.001*

0.98 (0.97–0.99)

0.001**

mMGMT

0.60 (0.46–0.78)

0.001**

0.47 (0.35–0.62)

0.001*

0.47 (0.35–0.63)

0.001**

PTEN mutation

0.98 (0.62–1.53)

0.918

1.02 (0.65–1.62)

0.921

1.01 (0.64–1.59)

0.974

EGFR gene amplification

0.82 (0.63–1.07)

0.149

0.87 (0.65–1.16)

0.344

0.86 (0.64–1.15)

0.3

TERTp mutation

1.11 (0.82–1.49)

0.481

1.03 (0.76–1.38)

0.872

1.02 (0.76–1.38)

0.877

EOR

0.90 (0.68–1.19)

0.458

0.87 (0.65–1.16)

0.333

0.85 (0.64–1.14)

0.287

  1. CI confidence interval, TMT temporal muscle thickness, KPS Karnofsky Performance Scale, mMGMT methylation of O6-methylguanine-DNA methyltransferase promoter, PTEN phosphatase and tensin homolog, EGFR epidermal growth factor, TERTp telomerase reverse transcriptase promoter, EOR extent of resection, OS overall survival, PSM propensity score matching.
  2. Note: Asterisks (*) indicate statistical significance (*p < 0.05; **p < 0.01); bold indicates the odds ratio of significant variables according to both univariable and multivariable Cox regression analysis.
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