Table 1 Overview of the GDP-modified compounds obtained according to general procedure C and the observed m/z values.
From: Targeting KRASG13C with cyclic linker based inhibitors to explore warhead orientation
Nucleotide |
| # | Exact Mass (calc.) | for [M-H]− | LC-MS (m/z) |
|---|---|---|---|---|---|
|
| 6a | 678.1 | C21H30N9O13P2− | 677.9 |
| 6f | 730.1 | C25H34N9O13P2− | 729.9 | |
| 6 g | 730.1 | C25H34N9O13P2− | 730.1 | |
| 6e | 786.2 | C29H42N9O13P2− | 786.1 | |
| 6b | 758.2 | C27H38N9O13P2− | 758.1 | |
| 6c | 758.2 | C27H38N9O13P2− | 758.1 | |
| 6 h | 758.2 | C27H38N9O13P2− | 758.1 | |
| 6i | 758.2 | C27H38N9O13P2− | 758.0 | |
| 6d | 786.2 | C29H42N9O13P2− | 786.1 |
