Fig. 6
Stella model for the dynamic simulation of the complex size change observed in CMPs after replacement of the buffer by pepsin-added SGF at pH 2. The volume changes of the particle are exclusively caused by volume flows - reduction via - IV1 or - IV3, which cause two shrinkage transitions and one an exponential decay, and enlargement via IV2, which leads to a two-step expansion. The start and duration of each process (chronology of events) are determined by characteristic times that define ramps and pulses. The optically observed particle area is calculated from the volume using spherical approximation.
