Table 3 Logistic regression analysis of the big five personality traits and thyroid Nodules.

From: Conscientiousness personality is associated with increased thyroid nodule risk and sleep quality plays a masking role in this association

Variables

Overall population(n = 331)

Aged < 45 years(n = 234)

Aged ≥ 45 years(n = 97)

OR[95%CI]

Bonferroni corrected P-value

OR[95%CI]

Bonfferroni corrected P-value

OR[95%CI]

Bonferroin corrected P-value

Neuroticism

Model1

1.035[0.996,1.075]

0.390

1.029[0.981,1.079]

1.240

1.049[0.981,1.122]

0.825

Model2

1.033[0.993,1.075]

0.540

1.025[0.976,1.076]

1.640

1.065[0.988,1.147]

0.495

Model3

1.029[0.987,1.072]

0.890

1.029[0.977,1.084]

1.410

1.095[0.997,1.202]

0.295

Extroversion

Model1

0.934[0.894,0.976]

0.010

0.934[0.884,0.987]

0.080

0.949[0.875,1.028]

1.000

Model2

0.952[0.908,0.998]

0.200

0.939[0.887,0.994]

0.155

0.966[0.885,1.055]

2.205

Model3

0.948[0.901,0.997]

0.190

0.930[0.873,0.991]

0.130

0.959[0.852,1.078]

2.405

Openness

Model1

1.002[0.957,1.050]

4.645

1.011[0.953,1.072]

3.605

1.009[0.926,1.098]

4.205

Model2

1.018[0.969,1.069]

2.415

1.014[0.955,1.077]

3.260

1.007[0.918,1.105]

4.405

Model3

1.008[0.957,1.061]

3.880

0.999[0.937,1.065]

4.910

0.962[0.855,1.081]

2.565

Agreeableness

Model1

1.032(0.981,1.086)

1.085

1.001[0.942,1.064]

4.860

1.106[1.000,1.223]

0.245

Model2

1.015[0.961,1.071]

3.015

0.992[0.930,1.057]

4.010

1.077[0.966,1.202]

0.915

Model3

1.001[0.945,1.061]

4.84

0.977[0.910,1.048]

2.575

1.065[0.925,1.227]

1.905

Conscientiousness

Model1

1.075[1.028,1.123]

0.005

1.091[1.034,1.151]

0.010

1.005[0.922,1.097]

0.470

Model2

1.060[1.011,1.111]

0.075

1.086[1.028,1.148]

0.015

1.000[0.910,1.098]

4.980

Model3

1.028[0.990,1.068]

0.735

1.110[1.043,1.181]

< 0.005

0.953[0.838,1.084]

2.325

  1. Model 1, unadjusted variables; Model 2, Adjusting gender and age; Model 3, Based on model 2, education background, occupation, smoking status, drinking status, hyperlipidemia, hypertension, blood glucose and BMI were further included.
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