Table 5 Estimation of activity spectra for substances (PASS) through Way 2 Drug server.

From: Computational and pharmacophore-based study of Camellia sinensis phytochemicals targeting BRAF in melanoma

Biological activities

Theaflagallin

Epiallocatechin 3-O-cinnamate

(-)-Epicatechin gallate

Pa

Pi

Pa

Pi

Pa

Pi

TP53 expression enhancer

0.974

0.003

0.922

0.004

0.939

0.004

Antimutagenic

0.927

0.002

0.975

0.001

0.935

0.002

Anticarcinogenic

0.841

0.004

0.891

0.003

0.843

0.004

Chemopreventive

0.831

0.003

0.929

0.002

0.866

0.003

Antioxidant

0.811

0.003

0.863

0.003

0.786

0.004

Free radical scavenger

0.804

0.003

0.953

0.001

0.939

0.001

Antineoplastic

0.803

0.011

0.758

0.017

0.643

0.036

Apoptosis agonist

0.798

0.008

0.811

0.007

0.724

0.013

Hepatoprotectant

0.786

0.004

0.871

0.003

0.811

0.004

Chemoprotective

0.604

0.005

0.631

0.004

0.576

0.005

Cardioprotectant

0.600

0.006

0.586

0.006

0.819

0.003

Antiinflammatory

0.580

0.036

0.648

0.023

0.611

0.029

Testosterone17beta-dehydrogenase (NADP +) inhibitor

0.614

0.085

0.401

0.184

0.641

0.075

Casapase 3 stimulant

0.531

0.023

0.533

0.023

0.534

0.023

Antineoplastic (breast cancer)

0.512

0.018

0.531

0.016

0.528

0.016

Proliferative diseases treatment

0.674

0.007

0.823

0.003

0.731

0.005