Table 5 Estimation of activity spectra for substances (PASS) through Way 2 Drug server.
Biological activities | Theaflagallin | Epiallocatechin 3-O-cinnamate | (-)-Epicatechin gallate | |||
|---|---|---|---|---|---|---|
Pa | Pi | Pa | Pi | Pa | Pi | |
TP53 expression enhancer | 0.974 | 0.003 | 0.922 | 0.004 | 0.939 | 0.004 |
Antimutagenic | 0.927 | 0.002 | 0.975 | 0.001 | 0.935 | 0.002 |
Anticarcinogenic | 0.841 | 0.004 | 0.891 | 0.003 | 0.843 | 0.004 |
Chemopreventive | 0.831 | 0.003 | 0.929 | 0.002 | 0.866 | 0.003 |
Antioxidant | 0.811 | 0.003 | 0.863 | 0.003 | 0.786 | 0.004 |
Free radical scavenger | 0.804 | 0.003 | 0.953 | 0.001 | 0.939 | 0.001 |
Antineoplastic | 0.803 | 0.011 | 0.758 | 0.017 | 0.643 | 0.036 |
Apoptosis agonist | 0.798 | 0.008 | 0.811 | 0.007 | 0.724 | 0.013 |
Hepatoprotectant | 0.786 | 0.004 | 0.871 | 0.003 | 0.811 | 0.004 |
Chemoprotective | 0.604 | 0.005 | 0.631 | 0.004 | 0.576 | 0.005 |
Cardioprotectant | 0.600 | 0.006 | 0.586 | 0.006 | 0.819 | 0.003 |
Antiinflammatory | 0.580 | 0.036 | 0.648 | 0.023 | 0.611 | 0.029 |
Testosterone17beta-dehydrogenase (NADP +) inhibitor | 0.614 | 0.085 | 0.401 | 0.184 | 0.641 | 0.075 |
Casapase 3 stimulant | 0.531 | 0.023 | 0.533 | 0.023 | 0.534 | 0.023 |
Antineoplastic (breast cancer) | 0.512 | 0.018 | 0.531 | 0.016 | 0.528 | 0.016 |
Proliferative diseases treatment | 0.674 | 0.007 | 0.823 | 0.003 | 0.731 | 0.005 |