Table 1 Statistical analysis results for the two studies.
Metrics | Clinical study no. 1: Skin aging and comparison between two ethnic groups | Clinical study no. 2: Effect of an anti-aging product on fiber dermis | ||
|---|---|---|---|---|
Age effect Y (N = 33) vs. O (N = 27) | Ethnicity effect A (N = 27) vs. C (N = 33) | t0 vs. t1 (N = 31) | t0 vs. t3 (N = 24) | |
Number of connected and isolated fibers | Y = 652 ± 144 O = 648 ± 133 | A = 714 ± 147 C = 598 ± 107 | t0 = 412 ± 51 t1 = 399 ± 69 | t0 = 421 ± 53 t3 = 407 ± 47 |
Two-ways Anova F(1,57) = 0.133, p = 0.717 (NS) | Two-ways Anova F(1,57) = 12.362, p = 0.001 (S) | Paired t-test t(30) = 1.069, p = 0.294 (NS) | Paired t-test t(23) = 1.047, p = 0.306 (NS) | |
Number of connected fibers | Y = 151 ± 36 O = 147 ± 35 | A = 165 ± 39 C = 137 ± 26 | t0 = 97 [18] t1 = 87 [35] | t0 = 97 [28] t3 = 89 [25] |
Two-ways Anova F(1,57) = 0.004, p = 0.952 (NS) | Two-ways Anova F(1,57) = 11.240, p = 0.001 (S) | Wilcoxon signed rank test z(30) = 375, p = 0.012 (S) | Wilcoxon signed rank test z(23) = 248, p = 0.005 (S) | |
Number of isolated fibers | Y = 501 ± 111 O = 500 ± 102 | A = 549 ± 111 C = 462 ± 85 | t0 = 311 ± 37 t1 = 310 ± 48 | t0 = 316 ± 38 t3 = 317 ± 35 |
Two-ways Anova F(1,57) = 0.204, p = 0.653 (NS) | Two-ways Anova F(1,57) = 11.789, p = 0.001 (S) | Paired t-test t(30) = 0.155, p = 0.878 (NS) | Paired t-test t(23) = -0.071, p = 0.944 (NS) | |
Length of connected and isolated fibers | Y = 82 ± 19 O = 70 ± 18 | A = 81 ± 23 C = 73 ± 16 | t0 = 121 ± 32 t1 = 138 ± 40 | t0 = 115 ± 29 t3 = 133 ± 31 |
Two-ways Anova F(1,57) = 4.890, p = 0.031 (S) | Two-ways Anova F(1,57) = 1.413, p = 0.240 (NS) | Paired t-test t(30) = -2.089, p = 0.045 (S) | Paired t-test t(23) = -2.639, p = 0.015 (S) | |
Length of connected fibers | Y = 310 ± 98 O = 262 ± 82 | A = 308 ± 115 C = 273 ± 69 | t0 = 462 ± 151 t1 = 596 ± 227 | t0 = 431 ± 134 t3 = 580 ± 186 |
Two-ways Anova F(1,57) = 3.346, p = 0.073 (T) | Two-ways Anova F(1,57) = 1.417, p = 0.239 (NS) | Paired t-test t(30) = -2.966, p = 0.006 (S) | Paired t-test t(23) = -3.717, p = 0.001 (S) | |
Length of isolated fibers | Y = 14.62 ± 0.63 O = 14.28 ± 0.72 | A = 14.55 ± 0.72 C = 14.40 ± 0.66 | t0 = 13.87 ± 0.76 t1 = 13.36 ± 0.60 | t0 = 14.01 ± 0.80 t3 = 13.37 ± 0.71 |
Two-ways Anova F(1,57) = 3.408, p = 0.070 (T) | Two-ways Anova F(1,57) = 0.388, p = 0.536 (NS) | Paired t-test t(30) = 4.051, p = 0.000 (S) | Paired t-test t(23) = 3.155, p = 0.004 (S) | |
Number of nodes | Y = 1785 ± 710 O = 1463 ± 581 | A = 1890 ± 757 C = 1435 ± 515 | t0 = 1804 ± 494 t1 = 2116 ± 555 | t0 = 1717 ± 462 t3 = 2124 ± 497 |
|  | Two-ways Anova F(1,57) = 2.524, p = 0.118 (NS) | Two-ways Anova F(1,57) = 6.445, p = 0.014 (S) | Paired t-test t(30) = -2.783, p = 0.009 (S) | Paired t-test t(23) = -4.095, p = 0.000 (S) |
Density | Y = 0.00094 ± 0.00032 O = 0.00079 ± 0.00024 | A = 0.00099 ± 0.00032 C = 0.00077 ± 0.00023 | t0= 0.00190 ± 0.00037 t1=0.00206 ± 0.00038 | t0 = 0.00185 ± 0.00035 t3=0.00207 ± 0.00038 |
Two-ways Anova F(1,57) = 2.662, p = 0.108 (NS) | Two-ways Anova F(1,57) = 8.134, p = 0.006 (S) | Paired t-test t(30) = -1.861, p = 0.072 (T) | Paired t-test t(23) = -2.959, p = 0.007 (S) | |
Anisotropy score | Y = 0.280 ± 0.098 O = 0.332 ± 0.113 | A = 0.318 ± 0.104 C = 0.292 ± 0.111 | t0 = 0.554 ± 0.096 t1 = 0.499 ± 0.119 | t0 = 0.570 ± 0.095 t3 = 0.506 ± 0.098 |
Two-ways Anova F(1,57) = 4.250, p = 0.044 (S) | Two-ways Anova F(1,57) = 1.526, p = 0.222 (NS) | Paired t-test t(30) = 3.076, p = 0.004 (S) | Paired t-test t(23) = 3.324, p = 0.003 (S) | |
