Table 1 Characteristic at baseline between the survival and Non-survival group.

From: Machine learning models predict mortality risk in diabetic neuropathy patients using MIMIC-IV data

Variables

Total

Survival

Non-survival

P-value

(n = 1313)

(n = 812)

(n = 501)

Age(year)

65.85 ± 13.65

63.80 ± 13.53

69.18 ± 13.19

<0.001

Gender(%)

   

0.78

Male

769(58.57%)

478(58.87%)

291(58.08%)

 

Female

544(41.43%)

334(41.13%)

210(41.92%)

 

Comorbidity

    

Myocardial infarct, n(%)

   

0.067

Yes

409(31.15)

238(29.31)

171(34.13)

 

No

904(68.85)

574(70.69)

330(65.87)

 

Congestive heart failure, n(%)

   

<0.001

Yes

552(42.04)

295(36.33)

257(51.30)

 

No

761(57.96)

517(63.67)

244(48.70)

 

Chronic pulmonary disease, n(%)

   

0.024

Yes

337(25.67)

191(23.52)

146(29.14)

 

No

976(74.33)

621(76.48)

355(70.86)

 

Renal disease, n(%)

   

<0.001

Yes

595(45.32)

315(38.79)

280(55.89)

 

No

718(54.68)

497(61.21)

221(44.11)

 

Hypertension, n(%)

   

<0.001

Yes

490(37.32)

343(42.24)

147(29.34)

 

No

823(62.68)

469(57.76)

354(70.66)

 

Obesity, n(%)

   

0.001

Yes

302(23.00)

211(25.99)

91(18.16)

 

No

1011(77.00)

601(74.01)

410(81.84)

 

Laboratory parameters

    

Aniongap_min (mmol/L)

13.00(11.00, 15.00)

13.00(11.00, 15.00)

14.00(12.00,

<0.001

16.00)

Aniongap_max (mmol/L)

17.00(14.00, 21.00)

17.00(13.00, 20.00)

18.00(15.00,

<0.001

22.00)

Bicarbonate_min (mmol/L)

21.00(18.00, 24.00)

21.00(19.00, 23.00)

21.00(17.00, 24.00)

0.627

Bicarbonate_max (mmol/L)

24.00(22.00, 27.00)

24.00(22.00, 26.00)

24.00(21.00, 27.00)

0.055

Creatinine_min (mg/dL)

1.20(0.80,

1.10(0.80, 1.70)

1.40(0.95, 2.80)

<0.001

2.10)

Creatinine_max (mg/dL)

1.40(1.00, 2.60)

1.30(1.00, 2.10)

1.80(1.10, 3.30)

<0.001

BUN_min (mg/dL)

24.00(16.00, 39.00)

21.00(14.00, 33.00)

30.00(19.00, 47.50)

<0.001

BUN_max (mg/dL)

30.00(19.00, 49.00)

26.00(17.00, 42.00)

37.00(25.00, 58.00)

<0.001

Calcium_min (mmol/L)

8.17(7.80,

8.17(7.80, 8.60)

8.20(7.75, 8.60)

0.667

8.60)

Calcium_max (mmol/L)

8.69(8.20, 9.10)

8.69(8.20, 9.00)

8.69(8.20, 9.20)

0.275

Chloride_min (mmol/L)

101.00(96.00,105.00)

101.00(96.00, 105.00)

99.00(95.00, 103.00)

<0.001

Chloride_max (mmol/L)

105.03 ± 6.48

105.69 ± 6.23

103.97 ± 6.72

<0.001

Sodium_min (mmol/L)

136.00(133.00,139.00)

136.00(133.00

136.00(132.00,139.00)

0.337

,139.00)

Sodium_max (mmol/L)

139.00(137.00,142.00)

139.00(137.00

139.00(137.00,142.00)

0.929

,142.00)

Potassium_min (mmol/L)

4.04 ± 0.60

4.05 ± 0.58

4.03 ± 0.62

0.608

Potassium_max (mmol/L)

4.70(4.30,

4.70(4.30, 5.20)

4.70(4.20, 5.40)

0.693

5.30)

PTT_min (s)

28.80(25.90, 31.75)

28.00(25.40, 30.30)

30.24(27.00, 33.80)

<0.001

PTT_max (s)

32.90(28.30, 43.78)

31.80(27.80, 43.78)

35.10(29.10, 46.30)

<0.001

PT_min (s)

13.10(12.00, 14.45)

12.90(11.80, 14.30)

13.60(12.30, 15.75)

<0.001

PT_max(s)

14.40(12.70, 17.19)

14.20(12.60, 16.46)

14.80(12.80, 18.10)

<0.001

INR_min

1.20(1.10, 1.32)

1.20(1.10, 1.30)

1.20(1.10, 1.40)

<0.001

INR_max

1.30(1.10, 1.59)

1.30(1.10, 1.50)

1.30(1.20, 1.70)

<0.001

Glucose_mean(mg/dL)

163.00(133.49, 210.75)

156.92(131.55, 206.63)

170.75(138.45,214.80)

0.008

Hemoglobin_mean (g/dL)

10.34 ± 1.89

10.45 ± 1.87

10.15 ± 1.91

0.006

Platelets_mean (109/L)

195.33(144.29,256.42)

189.25(144.00

205.20(145.83,270.75)

0.065

,250.00)

WBC_mean (109/L)

11.26(8.25,

11.50(8.74,

11.03(7.48,

0.031

15.20)

15.12)

15.32)

RBC_mean (109/L)

3.53 ± 0.68

3.57 ± 0.68

3.46 ± 0.68

0.006

RDW_mean (%)

14.60(13.60, 16.05)

14.20(13.33, 15.45)

15.43(14.29, 16.90)

<0.001

Lymphocytes_mean (109/L)

3.69(1.27, 118.32)

2.55(1.27, 114.42)

55.10(1.26, 121.28)

0.028

Neutrophils_mean (109/L)

23.90(8.63, 831.30)

14.41(7.99, 734.92)

492.80(11.27,980.01)

<0.001

Monocytes_mean (109/L)

2.00(0.60, 43.64)

1.07(0.50, 38.05)

23.83(0.84, 48.76)

<0.001

Vital signs

    

Heartrate_mean (bpm)

83.81 ± 14.63

84.17 ± 13.83

83.23 ± 15.85

0.277

Meanbp_mean (mmHg)

75.70(70.15,

76.17(70.82,

74.81(69.26,

0.002

83.64)

84.03)

83.00)

Respiratory rate_mean

18.46(16.57,

18.14(16.56,

19.00(16.61,

0.001

(insp/min)

20.53)

20.09)

21.46)

Temperature_mean (℃)

36.84 ± 0.49

36.86 ± 0.44

36.82 ± 0.55

0.127

Organ scores

    

SAPS-â…¡

37.00 ± 13.24

34.93 ± 12.34

40.36 ± 13.94

<0.001

APS-â…¢

47.00(37.00, 62.00)

45.00(35.00, 57.00)

53.00(41.00, 69.00)

<0.001

LODS

5.00(3.00, 7.00)

4.00(3.00, 6.00)

5.00(3.00, 7.00)

<0.001

OASIS

30.00(25.00, 37.00)

29.00(24.00, 36.00)

32.00(26.00, 39.00)

<0.001

GCS

14.00(13.00, 15.00)

14.00(13.00, 15.00)

14.00(11.00, 15.00)

<0.001

CCI

7.80 ± 2.54

7.16 ± 2.37

8.85 ± 2.47

<0.001

Combination inflammatory indicators

    

NLR

6.80(3.89, 12.64)

5.89(3.67, 10.92)

8.79(4.75, 15.51)

<0.001

PLR

36.48(1.83, 148.66)

60.97(1.90, 150.88)

3.94(1.70, 141.01)

0.004

LMR

2.42(1.32, 4.14)

2.81(1.50, 4.54)

1.99(1.08, 3.30)

<0.001

PNR

6.58(0.25, 20.23)

11.78(0.29, 22.02)

0.41(0.21, 16.68)

<0.001

PWR

17.40(11.82, 24.92)

16.46(11.36, 23.69)

18.95(12.75, 26.68)

<0.001

SII

1341.68(671.58,2671.13)

1163.43(619.30,2286.32)

1667.08(815.11,3400.56)

<0.001

  1. Variables are initial values if not otherwise specified. _max means maximum variable, and _min means minimum variable during ICU.
  2. BUN, blood urea nitrogen; WBC, white blood cells; RBC, red blood cells; RDW, red blood cell distribution width; PTT, partial thromboplastin time; PT, prothrombin time; INR, international normalized ratio; Meanbp, mean blood pressure; SAPS-Ⅱ, simplified acute physiology score Ⅱ; APS-Ⅲ, acute physiology score Ⅲ; LODS, logistic organ dysfunction system; OASIS, oxford acute severity of illness score; GCS, Glasgow coma scale; CCI, charlson comorbidity index; NLR, neutrophil-lymphocyte ratio; PLR, platelet–lymphocyte ratio; LMR, lymphocyte-to-monocyte ratio; PNR, platelet–neutrophil ratio; PWR, platelet–white blood cells ratio; SII, systemic immune inflammation index.
  3. Table 1 was restructured to categorize variables by reporting format.
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