Fig. 11 | Scientific Reports

Fig. 11

From: SERPINA1 gene regulates the tumorigenesis and progression of breast cancer through PI3K/AKT signaling pathway and tumor immune microenvironment

Fig. 11

Cell proliferation assay to explore the effect of serpina1 gene on the proliferation of breast cancer cells. A. The results of cell proliferation experiment based on the real-time monitoring cell system showed that the proliferation rate of the overexpression group was lower than that of the control group (the green dotted line represents the cells of the control group, and the red dotted line represents the cells of the overexpression group); B. The results of cell proliferation experiment based on real-time monitoring cell system showed that the proliferation rate of the knockdown group was higher than that of the control group (green dotted line represents SI1 sequence knockdown group cells, blue dotted line represents SI2 sequence knockdown group cells); C. The results of plate cloning experiment showed that the proliferation ability of knockdown group was stronger than that of control group; D. The results of plate cloning experiment showed that the proliferation ability of the overexpression group was weaker than that of the control group. (* p < 0.05;**p < 0.01;***p < 0.001, ****p < 0.0001).

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