Table 3 Sensitivity analysis of the association between TyG index trajectory and the risk of hypertension.

From: Association between triglyceride glucose index trajectory and risk of hypertension in rural residents: a prospective cohort study

TyG index trajectories

Model 1

Model 2

Model 3

HR (95%CI)

P value

HR (95%CI)

P value

HR (95%CI)

P value

Excluded participants with diabetes at baseline (n = 8939)

Low stable

Reference

 

Reference

 

Reference

 

Moderate stable

1.68 (1.51–1.87)

< 0.001

1.55 (1.39–1.73)

< 0.001

1.39 (1.24–1.56)

< 0.001

High stable

2.37 (1.92–2.91)

< 0.001

2.09 (1.69–2.58)

< 0.001

1.63 (1.29–2.06)

< 0.001

Excluded participants taking hypoglycemic agents or lipid-lowering medications (n = 9265)

Low stable

Reference

 

Reference

 

Reference

 

Moderate stable

1.72 (1.54–1.91)

< 0.001

1.57 (1.41–1.75)

< 0.001

1.41 (1.26–1.58)

< 0.001

High stable

2.56 (2.14–3.07)

< 0.001

2.24 (1.86–2.70)

< 0.001

1.74 (1.41–2.14)

< 0.001

Excluded participants with family history of hypertension (n = 8481)

Low stable

Reference

 

Reference

 

Reference

 

Moderate stable

1.70 (1.52–1.89)

< 0.001

1.56 (1.39–1.74)

< 0.001

1.39 (1.24–1.57)

< 0.001

High stable

2.65 (2.21–3.17)

< 0.001

2.28 (1.90–2.74)

< 0.001

1.80 (1.47–2.21)

< 0.001

Multiple imputation (n = 9343)

Low stable

Reference

 

Reference

 

Reference

 

Moderate stable

1.72 (1.55–1.91)

< 0.001

1.57 (1.41–1.75)

< 0.001

1.43 (1.28–1.60)

< 0.001

High stable

2.69 (2.26–3.19)

< 0.001

2.32 (1.94–2.76)

< 0.001

1.86 (1.55–2.24)

< 0.001

  1. Model 1: unadjusted; Model 2: adjusted for sex, age, ethnicity, education, marital status, and annual income; Model 3: adjusted for sex, age, ethnicity, education, marital status, annual income, smoking status, drinking status, physical activity (MET-h/d), diet score, BMI, low-density lipoprotein cholesterol, high-density lipoprotein cholesterol, total cholesterol, and glomerular filtration rate. HR, hazard ratio.