Fig. 4
From: Modeling of lung-liver interaction during infection in a human fluidic organ-on-a-chip
Microbial stimulation of the lung module results in changes of liver cell transcriptome. (A–C) Representative heat maps of significantly differentially expressed genes of Huh-7 in the fluidic system connected to differentiated HBEC stimulated with bacteria after 24 h. (A) Changes in gene expression of Huh-7 after the addition of unstimulated HBEC (Li_control_24h vs. LiLu_control_24h), (B) the stimulation with NTHi (LiLu_24h vs. LiLu_N_24h), and (C) the stimulation with PAO1 (LiLu_24h vs. LiLu_P_24h).
