Table 3 Crude and adjusted (for antibiotic treatment) odds ratio of healthcare-associated infections (HAIs) in patients treated vs. those untreated with non-selective β-blockers (C07AA). Results of conditional logistic regression. Crude and adjusted (for antibiotic treatment) odds ratio of healthcare-associated infections (HAIs) in patients treated vs. those untreated with selective β1-blockers (C07AB). Results of conditional logistic regression.

From: Non-selective beta-blockers enhance resolution of induced infections in animals and healthcare-associated infections in humans

(a)

 

total

treated

non-treated

OR (95% CI)

P

aOR (95% CI)

P

All infections

cases

1756

5 (0.28%)

1751 (99.72%)

0.28 (0.09–0.87)

0.03

0.29 (0.10–0.90)

0.03

controls

3512

35 (1.00%)

3477 (99.00%)

Gram-negative

cases

371

1 (0.27%)

370 (99.73%)

0.26 (0.03–2.16)

0.21

0.26 (0.03–2.17)

0.21

controls

1484

15 (1.01%)

1469 (98.99%)

Gram-positive

cases

236

1 (0.42%)

235 (99.58%)

0.33 (0.04–2.69)

0.30

0.33 (0.04–2.69)

0.30

controls

944

12 (1.27%)

932 (98.73%)

(b)

 

total

treated

non-treated

OR (95% CI)

P

aOR (95% CI)

P

All infections

cases

1756

451 (25.68%)

1305 (74.32%)

1.18 (1.00–1.39)

0.04

1.20 (1.02–1.41)

0.03

controls

3512

801 (22.81%)

2711 (77.19%)

Gram-negative

cases

371

105 (28.30%)

266 (71.70%)

1.46 (1.11–1.90)

0.01

1.46 (1.12–1.90)

0.01

controls

1484

321 (21.63%)

1163 (78.37%)

Gram-positive

cases

236

57 (24.15%)

179 (75.85%)

1.14 (0.84–1.54)

0.41

1.13 (0.84–1.53)

0.42

controls

944

208 (22.03%)

736 (77.97%)

  1. OR = odds ratio; aOR = odds ratio adjusted for antibiotic treatment; CI = confidence interval.