Table 1 Angiographic, OCT, and histological findings in the overlapping and end-to-end groups at one month.

From: Minimally overlapping technique of bioresorbable scaffolds in a porcine coronary artery model: proof-of-concept study

 

Location

Overlapping group

End-to-end group

p-value*

Angiography

 §Luminal decrease rate (%)

1st BRS

8.73 ± 0.15

4.08 ± 1.43

0.029

Overlap lesion

24.82 ± 1.07

8.22 ± 0.32

< 0.001

2nd BRS

6.77 ± 0.38

5.03 ± 1.71

0.218

OCT findings

 Neointimal thickness (mm)

1st BRS

0.21 ± 0.01

0.2 ± 0.02

0.774

Overlap lesion

0.58 ± 0.11

0.22 ± 0.03

< 0.001

2nd BRS

0.24 ± 0.01

0.2 ± 0.08

0.312

 Stenosis area (%)

1st BRS

23.46 ± 0.74

22.74 ± 0.76

0.169

Overlap lesion

65.7 ± 1.02

20.62 ± 0.53

< 0.001

2nd BRS

24.8 ± 0.48

22.86 ± 0.63

0.154

Histology

 Inflammatory cell infiltration

(Degree)

1st BRS

1.7 ± 0.67

1.1 ± 0.31

0.02

Overlap lesion

2.7 ± 0.48

1.1 ± 0.32

< 0.001

2nd BRS

1.9 ± 0.87

1.1 ± 0.3

0.014

 Fibrin deposition

(Degree)

1st BRS

1.2 ± 0.42

1.3 ± 0.48

0.314

Overlap lesion

2.2 ± 0.42

1.4 ± 0.51

< 0.001

2nd BRS

1.8 ± 0.91

1.3 ± 0.48

0.073

 Thickness of neointima

(Degree)

1st BRS

1.8 ± 0.63

1.2 ± 0.42

0.024

Overlap lesion

4.2 ± 0.63

1.4 ± 0.51

< 0.001

2nd BRS

2.1 ± 0.56

1.5 ± 0.7

0.052

 Elastic lamina change (Degree)

Overlap lesion

2.0 ± 0.47

0.6 ± 0.51

< 0.001

 Apoptotic cells (Degree)

Overlap lesion

4.6 ± 0.51

2.1 ± 0.73

< 0.001

  1. Data are expressed as mean ± standard deviation. §The amount of change was calculated as the difference between post-procedural measurements and those obtained at the one-month follow-up. The remaining variables were obtained at follow-up. *Statistical analyses were performed using the two-sample t-test and Mann–Whitney U test, as appropriate.
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