Table 4 Bivariate logistic regression analysis of factors associated with hyperuricemia among non-dialysis CKD patients, Gondar, Ethiopia, 2024 (n = 189).
Variable | Category | Normal UA (n) | Hyperuricemia (n) | COR (95% CI) | p-value |
|---|---|---|---|---|---|
Sex | Female | 38 | 51 | 1.00 | – |
Male | 27 | 73 | 2.05 (1.10–3.82) | 0.023 | |
BMI (kg/m2) | 18.5–24.9 | 44 | 50 | 1.00 | – |
< 18.5 | 5 | 3 | 0.50 (0.12–2.20) | 0.360 | |
25–29.9 | 12 | 53 | 3.90 (1.85–8.20) | < 0.001 | |
≥ 30 | 4 | 18 | 3.30 (1.25–8.65) | 0.015 | |
eGFR (mL/min/1.73 m2) | ≥ 45 | 27 | 18 | 1.00 | – |
30–44 | 17 | 22 | 1.95 (0.80–4.65) | 0.130 | |
15–29 | 15 | 58 | 5.20 (2.20–12.3) | < 0.001 | |
< 15 (non-dialysis) | 6 | 26 | 6.00 (2.35–15.4) | < 0.001 | |
Proteinuria (g/day) | < 0.5 | 33 | 47 | 1.00 | – |
0.5–3.5 | 21 | 41 | 1.25 (0.65–2.45) | 0.510 | |
≥ 3.5 | 11 | 36 | 1.95 (0.95–4.05) | 0.070 | |
Triglyceride (mg/dL) | < 150 | 43 | 57 | 1.00 | – |
≥ 150 | 22 | 67 | 2.60 (1.40–4.90) | 0.002 | |
Total cholesterol (mg/dL) | < 220 | 49 | 87 | 1.00 | – |
≥ 220 | 16 | 37 | 1.50 (0.75–2.90) | 0.210 | |
Smoking | Non-smoker | 59 | 109 | 1.00 | – |
Ex-smoker | 4 | 9 | 1.40 (0.45–4.25) | 0.510 | |
Current smoker | 2 | 6 | 2.40 (0.60–9.50) | 0.190 | |
Comorbidity | No | 21 | 34 | 1.00 | – |
Yes | 44 | 90 | 0.70 (0.35–1.35) | 0.240 |
