Fig. 6 | Scientific Reports

Fig. 6

From: Nrf2 alleviates excessive deposition of extracellular matrix in mammary fibrosis through TGF/Smad and ROS signals

Fig. 6

Effects of Nrf2 on mitochondrial damage and autophagy in vitro. (A) Determination of ROS content. (B-D) Protein bands and analysis of Mfn2, Hsp60 and β-actin in mMECs. (E) Mito-Tracker Red was used to detect changes in mitochondrial membrane potential, 200 μm. (F-K) Protein bands and analysis of PHB2, LC3, P62, p-Parkin, Parkin, Pink1 and β-actin in mMECs. The data were presented as Mean ± SD. Three independent repeatable experiments were performed. ** represents P < 0.01, * represents P < 0.05.

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