Fig. 10 | Scientific Reports

Fig. 10

From: Ameliorative effect of folic acid and vitamin B12 against Ivermectin-induced hepatotoxicity, renal toxicity, oxidative stress and immunohistochemical changes in male albino rats

Fig. 10

Immunohistochemical staining for Bcl-2 protein expression in renal tissue sections of male albino rats. (a) Control group showing strong positive Bcl-2 immunoreactivity. (b) IVM-treated group demonstrating a marked loss of Bcl-2 expression, indicating reduced anti-apoptotic activity. (c) IVM + folic acid-treated group showing partial restoration of Bcl-2 expression. (d) IVM + vitamin B12-treated group exhibiting positive Bcl-2 staining comparable to the control. Black arrows indicate positive reactions. Scale bar = 100 μm.

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