Table 1 Changes in liver profile of the control group and experimental groups treated with Ivermectin alone or in combination with folic acid and/or vitamin B12 in adult male albino rats.

From: Ameliorative effect of folic acid and vitamin B12 against Ivermectin-induced hepatotoxicity, renal toxicity, oxidative stress and immunohistochemical changes in male albino rats

Parameters

ALT (U/L)

AST (U/L)

ALP (U/L)

ALB (U/L)

TP (U/L)

Ctrl group

39.7 ± 2.5b

103.9 ± 5.9b

218.0 ± 3.6a

3.7 ± 0.20a

5.9 ± 0.2a

IVM group

47.5 ± 1.7a

151.8 ± 3.5a

150.3 ± 6.5b

2.6 ± 0.14b

5.53 ± 0.1b

IVM + FA group

32.4 ± 7.9b

111.8 ± 3.1b

111.3 ± 6.4c

2.8 ± 0.09b

5.98 ± 0.3a

IVM + Vit. B12 group

44.8 ± 3.0a

111.6 ± 17.0b

160.8 ± 6.0b

2.6 ± 0.07 b

5.8 ± 0.1a

  1. Values are expressed as means ± S.D. Values with different superscript (a, b and c) in the same column are significantly different at P < 0.05. Ctrl group: Control group; IVM group: Ivermectin group; IVM + FA group: Ivermectin + Folic acid group; IVM + Vit. B12 group: Ivermectin + Vit. B12 group; ALB: Albumin; TP: Total protein.