Table 3 Treatment of matched pediatric and adult cohort with grade III Ependymoma.
Characteristics | Total (N = 2011) | Alive (N = 1504) | Mortality (N = 507) | P |
|---|---|---|---|---|
Surgery | 1672 (83%) | 1319 (88%) | 353 (70%) | < 0.001 |
Surgery Type | 0.729 | |||
Gross total resection | 1604 (96%) | 1267 (96%) | 337 (95%) | |
Subtotal resection | 68 (4%) | 52 (4%) | 16 (5%) | |
Chemotherapy | 356 (18%) | 175 (12%) | 181 (37%) | < 0.001 |
Radiation | 640 (33%) | 356 (24%) | 284 (56%) | < 0.001 |
Adjuvant | 478 (75%) | 286 (78%) | 192 (68%) | |
Radiation Alone | 162 (25%) | 70 (22%) | 92 (32%) | |
Radiation Modality | 0.065 | |||
3D Conformal Therapy | 70 (11%) | 44 (12%) | 26 (9%) | |
External Beam | 408 (64%) | 218 (60%) | 190 (69%) | |
Intensity Modulated Therapy | 146 (23%) | 95 (26%) | 51 (19%) | |
Stereotactic | 11 (2%) | 7 (2%) | 4 (1%) | |
Unknown | 5 (1%) | 2 (< 1%) | 3 (1%) | |
Type of Radiation | 0.030 | |||
Photon | 561 (97%) | 350 (96%) | 271 (99%) | |
Proton | 19 (3%) | 16 (4%) | 3 (1%) | |
Fractions | 22.2 ± 15.3 | 22 ± 17.4 | 22.4 ± 11.7 | 0.728 |
Total Dose (cGy) | 4139.6 ± 1467.8 | 4228 ± 1400.4 | 4019.6 ± 1549.3 | 0.084 |
