Table 2 Subgroup analyse of OBI in HBcAb-positive population.
Subgroups | Study(n) | Pooled estimates of OBI (95% CI) | Heterogeneity (I2%) | P-value |
|---|---|---|---|---|
HBV prevalence | P = 0.05 | |||
Low-endemic regions | 18 | 3% (1, 7%) | 97% | |
Intermediate/high-endemic regions | 24 | 10% (4, 18%) | 98% | |
HBcAb-positive rate | P = 0.05 | |||
[0, 10) % | 12 | 2% (0, 5%) | 97% | |
[10, 30) % | 14 | 7% (2, 13%) | 97% | |
[30, 100) % | 14 | 13% (4, 25%) | 97% | |
Detection method | P = 0.17 | |||
Nested PCR | 13 | 9% (4, 17%) | 96% | |
Real-time qPCR | 23 | 5%(2, 8%) | 97% | |
HBsAb status | P = 0.96 | |||
HBsAb-positive | 22 | 8%(3, 16%) | 97% | |
HBsAb-negative | 22 | 8%(3, 16%) | 95% | |
Year of publication | P = 0.44 | |||
2000–2010 | 13 | 9% (3, 19%) | 98% | |
2011–2015 | 13 | 8% (1, 19%) | 97% | |
2016–2024 | 16 | 4% (2, 8%) | 97% | |
Population | P = 0.82 | |||
Blood donors | 30 | 6% (3, 11%) | 98% | |
Other general population | 12 | 7% (2, 16%) | 96% |