Table 3 Subgroup analyse of OBI in HBcAb-negative population.
Subgroups | Study(n) | Pooled estimates of OBI (95% CI) | Heterogeneity (I2%) | P-value |
|---|---|---|---|---|
HBV prevalence | P = 0.30 | |||
Low-endemic regions | 3 | 1% (0, 4%) | 79% | |
Intermediate/high-endemic regions | 11 | 2% (0, 6%) | 93% | |
HBcAb-positive rate | P < 0.01 | |||
[0, 10) % | 1 | 0% (0, 1%) | - | |
[10, 30) % | 6 | 2% (0, 4%) | 93% | |
[30, 100) % | 7 | 3% (0, 8%) | 93% | |
Detection method | P = 0.11 | |||
Nested PCR | 6 | 4% (0, 10%) | 94% | |
Real-time qPCR | 6 | 1%(0, 2%) | 70% | |
HBsAb status | P = 0.91 | |||
HBsAb-positive | 6 | 2%(0, 6%) | 90% | |
HBsAb-negative | 9 | 2%(0, 5%) | 91% | |
Year of publication | P = 0.04 | |||
2000–2010 | 5 | 6% (2, 12%) | 93% | |
2011–2015 | 4 | 0% (0, 2%) | 77% | |
2016–2024 | 5 | 1% (0, 4%) | 89% | |
Population | P = 0.39 | |||
Blood donors | 5 | 1% (0, 4%) | 89% | |
Other general population | 9 | 3% (0, 6%) | 93% |