Fig. 7 | Scientific Reports

Fig. 7

From: Mechanism of the traditional Chinese medicine SMBJ alleviates diabetes mellitus-induced Leydig cell dysfunction in rats testes

Fig. 7

SMBJ promotes R2C testosterone secretion. (A) and (B) The western blot of StAR in R2C cell treated with Glu, si-METTL3, SMBJ and data shown are mean ± standard deviation (n = 3). *P < 0.05, **P < 0.01, ***P < 0.001. (C) R2C cell testosterone levels (n = 3). *P < 0.05, **P < 0.01, ***P < 0.001, ****P < 0.0001. (D) and (E) The western blot of StAR in R2C cell treated with si-METTL3, SMBJ, PI3K inhibitor LY294002 and data shown are mean ± standard deviation(n = 3). *P < 0.05, **P < 0.01, ***P < 0.001. (F) R2C cell testosterone levels treated with si-METTL3, SMBJ, PI3K inhibitor LY294002 (n = 3). *P < 0.05, ***P < 0.001.

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