Fig. 5

Machine learning-based key gene selection for diagnostic biomarkers. (A) LASSO regression identified nine significant genes. (B) Random Forest selected the top ten important genes. (C) SVM-RFE identified thirteen significant genes. (D) Venn diagram showing eight core genes shared by all methods. (E) Correlation plot of the eight core genes (red: positive, green: negative). (F) ROC curves for the eight core genes, indicating strong diagnostic potential.