Table 1 The top ten differentially expressed (DE) proteins based on ascending adjusted p-values for each comparison are presented.

From: Sex-dependent modulation of PCB-mediated toxicity from a proteomic and microbiome perspective

Accession number

Description/protein name

Log2FC

p-Not Adj

p-Adj

MCON vs. FCON

P97501

Flavin-containing monooxygenase 3, GN=Fmo3

3.7812

0E-04

0E-04

P15392

Cytochrome P450 2A4, GN=Cyp2a4

3.3609

0E-04

0E-04

P12790

Cytochrome P450 2B9, GN=Cyp2b9

2.3984

0E-04

0E-04

Q9QYR7

Acyl-coenzyme A thioesterase 3, GN=Acot3

2.2152

0E-04

0E-04

G3X982

Aldehyde oxidase 3, GN=Aox3

−1.2621

0E-04

0E-04

P11714

Cytochrome P450 2D9, GN=Cyp2d9

−2.0058

0E-04

0E-04

Q8K182

Complement component C8 alpha chain, GN=C8a

−2.0154

0E-04

0E-04

Q5FW60

Major urinary protein 20, GN=Mup20

−2.3071

0E-04

0E-04

P19157

Glutathione S-transferase P 1, GN=Gstp1

−2.4968

0E-04

0E-04

Q91WL5

Cytochrome P450 4A12A, GN=Cyp4a12a

−2.9727

0E-04

0E-04

MPCB vs. FPCB

P97501

Flavin-containing monooxygenase 3, GN=Fmo3

4.1401

0E-04

0E-04

P15392

Cytochrome P450 2A4, GN=Cyp2a4

3.5552

0E-04

0E-04

Q9QYR7

Acyl-coenzyme A thioesterase 3, GN=Acot3

2.2881

0E-04

0E-04

P56657

Cytochrome P450 2C40, GN=Cyp2c40

1.7782

0E-04

0E-04

P12790

Cytochrome P450 2B9, GN=Cyp2b9

1.6760

0E-04

0E-04

Q63880

Carboxylesterase 3 A, GN=Ces3a

−1.0799

0E-04

0E-04

P28665

Murinoglobulin-1, GN=Mug1

−1.1592

0E-04

0E-04

Q9DBW0

Cytochrome P450 4V2, GN=Cyp4v2

−1.2969

0E-04

1E-03

G3X982

Aldehyde oxidase 3, GN=Aox3

−1.3964

0E-04

0E-04

Q8BH35

Complement component C8 beta chain, GN=C8b

−1.9306

0E-04

0E-04

MCON vs. MPCB

P00186

Cytochrome P450 1A2, GN=Cyp1a2

3.3404

0E-04

0E-04

P00184

Cytochrome P450 1A1, GN=Cyp1a1

3.1634

0E-04

0E-04

O55071

Cytochrome P450 2B19, GN=Cyp2b19

3.9063

0E-04

8.2E-03

O88833

Cytochrome P450 4A10, GN=Cyp4a10

0.8384

0E-04

8.2E-03

P20852

Cytochrome P450 2A5, GN=Cyp2a5

1.7485

0E-04

9.7E-03

Q64458

Cytochrome P450 2C29, GN=Cyp2c29

2.0350

0E-04

1.25E-02

P56395

Cytochrome b5, GN=Cyb5a

0.8788

0E-04

2.21E-02

Q00724

Retinol-binding protein 4, GN=Rbp4

0.7441

1E-03

3.55E-02

FCON vs. FPCB

P00186

Cytochrome P450 1A2, GN=Cyp1a2

3.0604

0E-04

0E-04

P00184

Cytochrome P450 1A1, GN=Cyp1a1

2.4387

0E-04

0E-04

Q9Z2G9

Oxidoreductase HTATIP2, GN=Htatip2

1.3564

0E-04

2.83E-02

  1. The first experimental group mentioned in each comparison serves as the reference group.
  2. Note: Accession number is based on UniProt Protein ID. Significance is set at p <0.05 for unadjusted and p <0.10 for adjusted. Abbreviation: GN, gene name; FC, fold change.