Fig. 2

Comparison of the observed time-course data (mean ± SD) to simulated concentrations in the metabolically active pool (MAP) and metabolically detoxified pool (MDP) of (A–L) liver, (M–X) kidneys and (Y–AJ) intestines in grass crap exposed to 0.03, 0.1, and 0.3 µg mL−1 CuNPs of 40–60 and 60–80 nm. Circular and diamond markers represent experimental data for MAP and MDP, respectively. Orange and green shaded areas with solid lines indicate simulated concentrations for MAP and MDP, respectively, along with 95% confidence intervals. Data are shown as mean ± SD; n = 5 unless noted (See Table S2 for condition with n = 4).