Fig. 1

(a) Correlation between [11C]PiB SUVr and [1⁸F]flutemetamol SUVr values processed using the Neurona PET pipeline in 74 subjects from the GAAIN dataset. WC was used as the reference region. Data points labeled “YHC” represent young healthy controls, while “Other” refers to patients with dementia (including both AD and non-AD etiologies). This correlation was used to derive the slope and intercept for PiB-equivalent SUVr transformation. (b) Linear equation for direct conversion of flutemetamol SUVr to CL based on the PiB-equivalent SUVr transformation derived from Fig. 1a.