Table 1 Clinical characteristics and standard semen parameters.

From: Identifying potential genetic biomarkers for sperm dysfunction through whole-genome sequencing

Sample ID

Age (years)

Volume (ml)

pH

Sperm count (million/ml)

Progressive motility (PR, %)

Non-progressive motility (NP, %)

Immotile (IM, %)

Morphology (%)

Vitality (%)

IVF outcome parameters

Female partner hormonal parameters

Embryo quality grade

β-hCG

FSH (mIU/ml)

LH (mIU/ml)

PRL (ng/ml)

Male partner sperm parameters (SDIG n= 9) 

290

46

6.2

7.7

1.2

52

7

41

2

67

1G2/1G3

Negative

11

17

22.4

220

40

2.6

7.5

3.7

48

6

46

2.5

55

1G1/2G2

Negative

5.5

7.8

7.0

279

37

3.2

8.0

4.2

22

9

69

2.5

44

1G1/2G2

Positive

9.7

12

15.2

271

45

2.9

7.8

7.6

26

12

62

2

44

2G2/1G3

Negative

8.4

6.5

9.8

201

35

3.2

8.0

7.8

33

12

55

2

55

2G1/1G2

Positive

6.6

9.2

8.0

285

39

6.2

7.8

10

52

6

42

2

73

1G2/1G3

Negative

11

9

11.5

203

34

4.9

8.5

11

33

14

53

1.5

52

1G1/2G2

Positive

5.2

7.1

8.8

287

48

4.0

7.5

12

24

4

72

2

55

No cleavage

Negative

9.1

12

7.8

282

30

2.3

8.3

18.5

20

9

71

2

55

2G2/1G3

Negative

4.2

11

21.4

Mean ± SD

39.33 ± 5.70

3.94 ± 1.41

7.90 ± 0.32

8.44

± 4.91

34.44 ±

12.24

8.78

± 3.15

56.78 ± 11.60

2.06 ± 0.28

55.56 ± 8.92

  

7.86 ± 2.42

10.18 ± 3.07

12.43 ± 5.57

Male partner sperm parameters (NG n = 8)

270

30

3.3

8

54

58

5

37

4

69

IUI

Negative

4.3

9.1

8

175

34

7.7

7.8

58

61

11

28

4

77

IUI

Positive

7.8

5.4

7

251

34

2.0

7.7

62.3

32

6

62

5

74

IUI

Negative

8

3.8

14

280

33

2.2

8.0

69

58

16

26

4

82

IUI

Negative

7

9

20.1

275

42

4.9

7.7

71

46

8

46

4

55

IUI

Negative

12

15

21.5

286

39

1.9

7.7

82

41

4

55

5

72

IUI

Negative

9.8

12

10.3

281

35

1.8

8.0

95

47

5

48

4

60

IUI

Negative

7.8

11

21

274

29

6.4

8.0

96

46

8

46

4

63

IUI

Positive

7.8

5.4

9.5

Mean ± SD

34.50 ± 4.03

3.78 ± 2.15

7.86 ± 0.14

73.41 ± 15.05

48.62 ± 9.22

7.88 ± 3.72

43.50 ± 11.70

4.25 ± 0.43

69.00 ± 8.51

  

8.06 ± 2.06

8.84 ± 3.57

13.93 ± 5.72

p-value

0.076

0.862

0.770

< 0.001

0.022

0.623

0.044

< 0.001

0.009

  

0.860

0.452

0.617

  1. Values are expressed as mean ± standard deviation (SD) unless otherwise indicated. Comparisons between the SDIG (Sperm Dysfunction Infertility Group, n = 9) and NG (Normozoospermic Group, n = 8) were performed using the Mann–Whitney U test for continuous variables. A p-value < 0.05 was considered statistically significant.
  2. SDIG, Sperm Dysfunction Infertility Group; NG, Normozoospermic Group; β-hCG, Beta human chorionic gonadotropin; FSH, Follicle-stimulating hormone; LH, Luteinizing hormone; PRL, Prolactin; G1, Embryo Quality Grade 1; G2, Embryo Quality Grade 2; G3, Embryo Quality Grade 3; IUI, Intrauterine Insemination.
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