Table 6 Antiviral activity for P. harmala leaves extract and its nano-formulations by plaque reduction assay method.
Sample code | CC50 (µg/mL) | Conc. (µg/mL) | Virus control (PFU/mL) | Viral count after treatment (PFU/mL) | Viral inhibition (%) |
|---|---|---|---|---|---|
P. harmala-CS NPs | 50 | 1.85 × 107 | 1.0 × 107 | 45.9 | |
575.4 | 25 | 1.15 × 107 | 37.8 | ||
12.5 | 1.3 × 107 | 29.7 | |||
6.25 | 1.5 × 107 | 18.9 | |||
P. harmala-ZnO NPs | 50 | 0.95 × 107 | 48.6 | ||
165.75 | 25 | 1.1 × 107 | 40.5 | ||
12.5 | 1.25 × 107 | 32.4 | |||
6.25 | 1.35 × 107 | 27 | |||
P. harmala-CS-ZnO NPs | 50 | 0.85 × 107 | 54.1 | ||
271.4 | 25 | 0.9 × 107 | 51.4 | ||
12.5 | 1.0 × 107 | 44.9 | |||
6.25 | 1.2 × 107 | 35.1 | |||
P. harmala-TPP-CS-ZnO NPs | 50 | 0.9 × 107 | 51.4 | ||
240.5 | 25 | 1.1 × 107 | 40.5 | ||
12.5 | 1.2 × 107 | 35.1 | |||
6.25 | 1.4 × 107 | 24.3 | |||
P. harmala extract | 50 | 1.35 × 107 | 27 | ||
407.6 | 25 | 1.4 × 107 | 24.3 | ||
12.5 | 1.45 × 107 | 21.6 | |||
6.25 | 1.5 × 107 | 18.9 | |||
Blank ZnO NPs | 92.95 | 50 | 1.5 × 107 | 24.3 | |
25 | 1.55 × 107 | 18.9 | |||
12.5 | 1.6 × 107 | 13.5 | |||
6.25 | 1.7 × 107 | 8.1 |
