Table 2 Summary of overall survival analysis - restricted mean (rmean) survival time, Kaplan-Meier analysis, univariate Cox regression. Significant p values (< 0.05) in bold.
Marker | Status | N | deaths | rmean | Median | p (Kaplan Meier) | HR univariate Cox regression (95% CI) | p |
|---|---|---|---|---|---|---|---|---|
GATA3 3-year follow-up | Low (< 0.5) | 60 | 27 | 2.72 | 2.25 | 0.006 | 2.08 (1.22, 3.57) | 0.007 |
High (≥ 0.5) | 85 | 31 | 3.61 | NA | ||||
GATA3 5-year follow-up | Low (< 0.5) | 60 | 30 | 2.81 | 2.40 | 0.04 | 1.69 (1.02, 2.78) | 0.042 |
High (≥ 0.5) | 85 | 31 | 3.63 | NA | ||||
GATA3 10-year follow-up | Low (< 0.5) | 60 | 30 | 2.81 | 2.40 | 0.014 | 1.82, (1.12, 2.94) | 0.016 |
High (≥ 0.5) | 85 | 31 | 3.63 | NA | ||||
IMP3 5-year follow-up | Low (< 0.75) | 74 | 28 | 3.58 | NA | 0.13 | 1.48 (0.89, 2.44) | 0.13 |
High (≥ 0.75) | 71 | 33 | 3.06 | 4.04 | ||||
HIF-1-α 5-year follow-up | Low (< 2.75) | 116 | 50 | 3.23 | 4.33 | 0.38 | 0.75 (0.39, 1.44) | 0.4 |
High (≥ 2.75) | 29 | 11 | 3.68 | NA | ||||
CK7 5-year follow-up | Low (< 3.25) | 129 | 54 | 3.38 | 4.70 | 0.31 | 1.46 (0.69, 3.07) | 0.3 |
High (≥ 3.25) | 16 | 8 | 2.78 | 3.82 | ||||
CA-IX 5-year follow-up | Low (< 8.75) | 126 | 52 | 3.38 | NA | 0.26 | 1.53 (0.73, 3.22) | 0.3 |
High (≥ 8.75) | 17 | 8 | 2.73 | 2.40 | ||||
High (> 0) | 65 | 30 | 3.18 | 4.08 |
