Fig. 2 | Scientific Reports

Fig. 2

From: Peptidylarginine deiminase 2 contributes to pathogenesis in trinitrobenzenesulfonic acid-induced colitis through macrophage extracellular trap-independent pathways

Fig. 2

Expression of inflammatory cytokines, chemokines, and PAD2 in PAD2KO mice. (a) TNFα, (b) IL-1β, (c) IL-12, (d) IL-23, (e) IFNγ, (f) CXCL2, and (g) PAD2 mRNA expression were determined using qRT-PCR in colon tissues of vehicle (30% ethanol)-, or TNBS-injected WT and PAD2KO mice on day 3, and mRNA levels were normalized to TBP. Data are presented as the means ± S.E.M. (n = 8–10). ####P < 0.0001, ###P < 0.001, ##P < 0.01 vs. vehicle-injected mice (WT EtOH), and ****P < 0.0001, *P < 0.05 vs. TNBS-injected mice (WT TNBS).

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