Table 3 Associations between FLNA staining intensity and SSTR2, SSTR5, E-Cadherin IRS, Ki-67 index, granulation pattern subtype.

From: Immunohistochemical analysis of filamin a expression in acromegaly and its correlation with tumor characteristics and treatment response

Parameter

FLNA- weak (1)

FLNA- moderate (2)

FLNA – strong (3)

p value

Ki-67 index median (min-max)

0.5 (0–1.25)

0.5 (0–2)

0.5 (0–1.5)

0.930

SSTR2 IRS- median (min-max)

9 (2–12)

9 (4–12)

12 (4.5–12)

0.640

SSTR5 IRS- median (min-max)

8 (2–8)

12 (8–12)

12 (4–12)

0.031*

E-Cadherin IRS- median (min-max)

3 (0.75–8)

1 (0–6)

4 (0–12)

0.241

CK- DG- number (%)

CK- SG- number (%)

5 (35.7%)

5 (35.7%)

4 (28.6%)

0.439

6 (35.3%)

9 (52.9%)

2 (11.8%)

  1. *- Kruskall-Wallis test was applied, p < 0.05.
  2. SSTR- somatostatin receptor, CK- cytokeratin, DG- densely granulated, SG- sparsenly granulated, FLNA- Filamin A.
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