Fig. 12 | Scientific Reports

Fig. 12

From: The dynamic regenerative scaffold stenting and shielding hernia system for dissection-free, atraumatic hernioplasty. Results of an experimental animal study

Fig. 12

(A) Tissue sample removed from the 3D scaffold of the S&D device six months implantation. Numerous clusters of intense neo-angiogenesis (colored in brown) with well-developed vascular structures are clearly evident close to the device fabric (X). CD31 50X—(B) Tissue sample excised from the 3D scaffold of the S&S device 8 months post-surgery. Numerous venous elements showing well-constituted muscular layer are highlighted close to the scaffold fabric (X). SMA 100X—The high magnification microphotograph in the right upper corner depicts two arterial structures with a well-represented muscular layer (colored in brown). SMA 200X—(C) Biopsy sample excised from the scaffold of the S&S device 6 months post implantation. The image shows plenty of muscular elements (colored in brown) grouped in bundles close to the TPE structure of the device. NGF 25X—(D) Biopsy specimen excised from the 3D scaffold of the S&S device 6 months post-implantation. The image shows a mature elongated nervous structure (colored in brown) developed within the TPE scaffold. NGFRp75 100X.

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