Fig. 1 | Scientific Reports

Fig. 1

From: Empirical phenotyping of joint patient-care data supports hypothesis-driven investigation of mechanical ventilation consequences

Fig. 1

Broad pipeline organization. Raw data (1) are digitally parametrized (2) over short windows, typically satisfying stationarity assumptions. Distributional parameter estimates are summarized and augmented with the contextual data of ventilator settings (3) which include information such as ventilator operation mode, positive-end expiratory pressure (PEEP) or other baseline pressure, flow and pressure triggers, and minimum mandatory breath rate. Feature vectors, defined by the augmented LVS descriptors, are reduced to three dimensions (4) where they can be analyzed based on time ordering (top) and structural similarity via segmentation (bottom). Finally, in (5), temporal evolution of the system is compactly encoded in the time-ordered LVS descriptor labels and their associated waveform characterizations in an interpretable and explainable way. The process transforms raw data (1) into a more easily comprehensible form (5).

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