Fig. 4
From: Identification and mechanism of key genes in inflammatory response of chronic otitis media in rats
Machine learning-based identification of key biomarker genes. (a) Support vector machine recursive feature elimination (SVM-RFE) analysis showing cross-validation results with the optimal gene number. (b–c) Least absolute shrinkage and selection operator (LASSO) regression analysis conducted using the glmnet package with (b) coefficient paths and (c) cross-validation plot. (d) Venn diagram showing the intersection of the SVM-RFE and LASSO results, identifying 3 key genes.(e) Receiver operating characteristic curve analysis using the pROC package evaluating the diagnostic effectiveness of the three key genes.
