Fig. 3 | Scientific Reports

Fig. 3

From: Eltrombopag olamine induces apoptosis in human breast adenocarcinoma and hepatocellular carcinoma cells through modulation of multiple apoptotic pathways

Fig. 3

Detection of early and late apoptosis using FITC-annexin V/PI staining. (A) and (B) show the detection of early and late apoptosis in MCF-7 and SMMC-7721 cells, respectively, using fluorescence microscopy. Images were captured at 20× magnification. A white scale bar (50 μm) is shown in the control or treatment images. (C) and (D) show flow cytometry results for MCF-7 and SMMC-7721 cells, respectively. “co” represents control cells and “tr” represents Eltrombopag olamine treated cells. Flow cytometry quadrants Q1-LL, Q1-LR, Q1-UR, and Q1-UL indicate live cells, early apoptotic cells, late apoptotic cells, and necrotic cells, respectively.

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