Fig. 4 | Scientific Reports

Fig. 4

From: Eltrombopag olamine induces apoptosis in human breast adenocarcinoma and hepatocellular carcinoma cells through modulation of multiple apoptotic pathways

Fig. 4

Effects of Eltrombopag olamine on the expression of several genes in MCF-7 and SMMC-7721 cells as detected by real-time PCR. (A) Relative mRNA expression of FAS, TP53, BAX, TNFα, Cytochrome-C (Cyt-C), NOTCH, EGFR and ERK genes in MCF-7 cells; (B) expression levels of TNFα, TP53, BAX, STAT3, MAPK, NOTCH, PARP1, EGFR and ERK genes in SMMC-7721 cells. The black dotted line indicates the 1.0 expression level.

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