Fig. 1 | Scientific Reports

Fig. 1

From: snRNA-seq reveals key transcription factors in the inflammatory response of microglia after intracerebral hemorrhage

Fig. 1

Single nucleus RNA-seq analysis of brain tissue of mouse recapitulates transcriptome atlas in ICH. (A) Graphical diagram of single nucleus isolation and RNA-seq experimental setup. (B) UMAP plot of composite single-cell transcriptomic profiles from all 4 samples. Sample origin, cell clustering, and cell annotation results are shown from left to right. (C) Bar plot comparing the proportions of cell populations of each cell type within each sample group. (D) Unsupervised clustering heatmap showing the expression of representative genes annotated by cell types in each cell type. (E) UMAP showing the expression of selected marker genes. Oligodendrocyte Progenitor Cells (OPC).

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