Table 1 The binding rate of the ester bond between mPEG and EDTA anhydride.

From: Ethylenediaminetetraacetic acid conjugated with polyethylene glycol is a safe chelator for colonic epithelial denudation and intestinal epithelial replacement therapy

Temperature (°C)

pH 4

pH 7

pH 8

25

97.2

99.1

95.6

40

104.2

101.9

96.0

50

102.6

102.0

99.0

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