Table 2 Comparison of biochemical parameters between metabolically healthy obese and metabolically unhealthy obese groups.

From: Metabolically healthy status in childhood obesity fails to protect against vitamin B12 deficiency

Parameters

Total obese group

Metabolically healthy obesity (n = 133)

Metabolically unhealthy obesity (n = 158)

p value

Triglycerides, mg/dL

118.2 (IQR 74–157)

77 (34–129)

143 (31–382)

0.001

HDL-C, mg/dL

46.6 (IQR 40–51)

49.8 (40–81)

44.0 (25–94)

0.001

Cholesterol, mg/dL

166.6 (IQR 139.2-180)

155 (73–236)

165 (76–265)

0.016

LDL-C, mg/dL

89.4 (IQR 73–106)

88.5 ± 25.4

89.5 ± 28.4

0.720

TG/HDL ratio

2.35 (IQR 1.46 − 3.58)

1.58 (0.45 − 2.98)

3.42 (0.43 − 9.09)

0.001

Glucose, mg/dL

92.2 (IQR 87–97)

90 (75–99)

94 (73–125)

0.001

Insulin, µIU/mL

24.8 (IQR 13.6–30.2)

17.3 (3.6–40)

24.5 (3.8-124.9)

0.001

HOMA-IR

5.7 (IQR 2.9 − 6.8)

3.9 (0.6–9.1)

5.6 (0.75 − 38.5)

0.001

HbA1c, %

5.4 (IQR 5.1–5.6)

5.3 (4.2–6)

5.5 (4–6.4)

0.821

TSH, mIU/mL

2.6 (IQR 1.75 − 2.36)

2.2 (0.5–6.7)

2.7 (0.1–8.4)

0.001

Free T4, ng/dL

1.07 (IQR 0.87 − 1.27)

1.06 ± 0.25

1.08 ± 0.24

0.406

ALT, U/L

28.4 (IQR 15–31)

18.5 (6–83)

23 (9-259)

0.002

AST, U/L

25.2 (IQR 18–28)

21.5 (11–60)

22 (11–151)

0.249

Uric acid, mg/dL

5.7 (IQR 4.5–6.8)

5.4 ± 1.47

5.9 ± 1.66

0.061

Vitamin B12, pgl/mL

287.3 (IQR 168–370)

255 (73–829.9)

264.5 (50–871)

0.696

25(OH)D, ng/mL

18.1 (IQR 12.5–22.5)

16.3 (6.4–60)

16.9 (4.9–40.2)

0.633

  1. Data are presented as mean ± SD or median [min–max] depending on distribution, and as percentage (%). Student’s t-test was used for normally distributed variables, and the Mann-Whitney U test for non-normal variables. Total group values are presented as median and interquartile range (25th–75th percentile). Statistically significant differences (p < 0.05) are indicated in bold and italic. Abbreviations: HDL-C, high-density lipoprotein cholesterol; LDL-C, low-density lipoprotein cholesterol; HOMA-IR, homeostasis model assessment of insulin resistance; TG: HDL-C, triglyceride-to-high-density lipoprotein cholesterol ratio.