Table 5 Associations between metabolic parameters and vitamin B12 deficiency: logistic regression results.

From: Metabolically healthy status in childhood obesity fails to protect against vitamin B12 deficiency

Variable

B-coefficient

p-value

Exp(B) (odds ratio)

95% CI (Lower–Upper)

Interpretation

AST

-0.109

0.011

0.897

0.94 − 0.99

↑ AST → ↓ B12 deficiency risk (negative assoc.)

Free T4

-7.237

< 0.001

0.001

0.01 − 0.032

↑ Free T4 → Strong ↓ B12 deficiency risk

Triglyceride

+ 0.052

0.032

1.054

0.97 − 1.11

↑ TG → ↑ B12 deficiency risk (positive assoc.)

HDL-C

-0.66

0.029

0.847

0.73–0.98

↑ HDL → ↓ B12 deficiency risk (negative assoc.)

TG/HDL-C ratio

-2.381

0.017

0.092

0.60–1.70

↓ TG/HDL → ↓ B12 deficiency risk

Uric acid

+ 0.400

0.047

1.491

0.96–1.5

↑ Uric acid → ↑ B12 deficiency risk

  1. Logistic regression analysis identifying biochemical predictors of vitamin B12 deficiency. B: regression coefficient, indicating the direction and magnitude of the association. Exp(B): odds ratio. Positive B values reflect increased risk, while negative values indicate decreased risk. Statistically significant associations (p < 0.05) are shown. ST4: free thyroxine, TG/HDL: triglyceride-to-HDL cholesterol ratio, HDL: high-density lipoprotein cholesterol.
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