Table 2 Single factor analysis after matching analysis.
OS | RFS | ||||||||
|---|---|---|---|---|---|---|---|---|---|
Variables | Value | N | Events | HR(95%CI) | P | N | Events | HR(95%CI) | P |
ATO | No | 57 | 15 | 1 | 57 | 14 | 1 | ||
Yes | 19 | 1 | 0.15(0.02, 1.1) | 0.03 | 19 | 2 | 0.32(0.07, 1.41) | 0.112 | |
Age | < 60 | 47 | 10 | 1 | 47 | 11 | 1 | ||
≥ 60 | 29 | 6 | 0.81(0.29, 2.23) | 0.682 | 29 | 5 | 0.62(0.22, 1.8) | 0.38 | |
Gender | Male | 14 | 1 | 1 | 14 | 2 | 1 | ||
Female | 62 | 15 | 3.21(0.42, 24.32) | 0.233 | 62 | 14 | 1.47(0.33, 6.49) | 0.607 | |
BMI | < 24 | 40 | 9 | 1 | 40 | 8 | 1 | ||
≥ 24 | 36 | 7 | 0.81(0.3, 2.18) | 0.68 | 36 | 8 | 1.05(0.39, 2.79) | 0.929 | |
Smoking | No | 56 | 14 | 1 | 56 | 11 | 1 | ||
Yes | 20 | 2 | 0.4(0.09, 1.76) | 0.209 | 20 | 5 | 1.29(0.45, 3.72) | 0.638 | |
Alcohol | No | 56 | 15 | 1 | 56 | 12 | 1 | ||
Yes | 20 | 1 | 0.17(0.02, 1.26) | 0.048 | 20 | 4 | 0.83(0.27, 2.58) | 0.745 | |
Diabetes | No | 42 | 10 | 1 | 42 | 8 | 1 | ||
Yes | 34 | 6 | 0.76(0.28, 2.09) | 0.594 | 34 | 8 | 1.26(0.47, 3.37) | 0.639 | |
Hypertension | No | 39 | 13 | 1 | 39 | 11 | 1 | ||
Yes | 37 | 3 | 0.2(0.06, 0.69) | 0.005 | 37 | 5 | 0.39(0.14, 1.13) | 0.073 | |
AFP | < 400 | 52 | 12 | 1 | 52 | 9 | 1 | ||
≥ 400 | 24 | 4 | 0.67(0.21, 2.08) | 0.482 | 24 | 7 | 1.71(0.63, 4.63) | 0.286 | |
BCLC stage | 0 or A | 62 | 10 | 1 | 62 | 12 | 1 | ||
B or C | 14 | 6 | 4.27(1.46, 12.5) | 0.004 | 14 | 4 | 2.38(0.73, 7.71) | 0.136 | |
Child pugh | A | 71 | 13 | 1 | 71 | 15 | 1 | ||
B | 5 | 3 | 7.48(2.04, 27.48) | < 0.001 | 5 | 1 | 1.78(0.23, 13.75) | 0.576 | |
Cirrhosis | No | 58 | 9 | 1 | 58 | 13 | 1 | ||
Yes | 18 | 7 | 3.18(1.18, 8.58) | 0.016 | 18 | 3 | 0.9(0.26, 3.19) | 0.876 | |
Clonorchissinensis | No | 66 | 15 | 1 | 66 | 14 | 1 | ||
Yes | 10 | 1 | 0.51(0.07, 3.9) | 0.513 | 10 | 2 | 1.04(0.24, 4.58) | 0.961 | |
Venous tumor thrombus | No | 66 | 12 | 1 | 66 | 13 | 1 | ||
Yes | 10 | 4 | 3.73(1.14, 12.2) | 0.019 | 10 | 3 | 2.72(0.74, 10.02) | 0.118 | |
Tumor number | 1 | 70 | 13 | 1 | 70 | 15 | 1 | ||
≥ 1 | 6 | 3 | 3.66(1.01, 13.21) | 0.034 | 6 | 1 | 0.98(0.13, 7.54) | 0.987 | |
Tumor size max | < 5 cm | 35 | 7 | 1 | 35 | 3 | 1 | ||
≥ 5 cm | 41 | 9 | 1.42(0.52, 3.86) | 0.489 | 41 | 13 | 4.84(1.37, 17.19) | 0.007 | |
Hepatitis | No | 22 | 4 | 1 | 22 | 6 | 1 | ||
HBV | 54 | 12 | 1.35(0.44, 4.19) | 0.601 | 54 | 10 | 0.7(0.25, 1.92) | 0.481 | |
MVI | No | 50 | 11 | 1 | 50 | 8 | 1 | ||
Yes | 26 | 5 | 1.11(0.38, 3.2) | 0.852 | 26 | 8 | 2.4(0.9, 6.44) | 0.073 | |
Duration of operation | < 240 | 37 | 6 | 1 | 37 | 6 | 1 | ||
≥ 240 | 39 | 10 | 1.78(0.65, 4.92) | 0.257 | 39 | 10 | 1.74(0.63, 4.79) | 0.282 | |
Bleeding | < 400 | 43 | 6 | 1 | 43 | 9 | 1 | ||
≥ 400 | 33 | 10 | 2.31(0.84, 6.37) | 0.095 | 33 | 7 | 1.05(0.39, 2.83) | 0.917 | |
Surgical approach | Open surgery | 59 | 12 | 1 | 59 | 14 | 1 | ||
Laparoscope | 17 | 4 | 1.13(0.37, 3.52) | 0.828 | 17 | 2 | 0.5(0.11, 2.18) | 0.343 | |
Radical resection | Yes | 51 | 9 | 1 | 51 | 7 | 1 | ||
No | 25 | 7 | 1.52(0.56, 4.09) | 0.407 | 25 | 9 | 2.62(0.98, 7.06) | 0.047 | |
